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CBD is a potent inhibitor of the enzyme CYP3A4. Celexa is metabolized in the liver mostly by CYP2C19, but also by CYP3A4 and CYP2D6. Potent inhibitors of CYP2C19 and 3A4 might decrease citalopram clearance. Your options are to switch medications or lower the dose.

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Aug 20, 2008 · How Long Does It Take For Celexa 20mg Qd To Work? When can I expect to feel reliel with the Celexa 20mg? Answer. Hi Lee, Thanks for your question.

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